Scientific Studies
Scientific Studies and Citations
- Gessi, A., Formaglio, P., Semeraro, B., Summa, D., Tamisari, E., & Tamburini, E. (2023). Electrolyzed Hypochlorous Acid (HOCl) Aqueous Solution as Low-Impact and Eco-Friendly Agent for Floor Cleaning and Sanitation. International journal of environmental research and public health,
20(18), 6712. https://doi.org/10.3390/ijerph20186712 - Williams, J., Rasmussen, E., Robins, L., & Nguyen, U. (2017). Hypochlorous Acid: Harnessing an Innate Response. Infect. Prev. Strategy (TIPS), 1-9.
- Edward, D. G., & Lidwell, O. M. (1943). Studies on air-borne virus infections: III. The killing of aerial suspensions of influenza virus by hypochlorous acid. The Journal of hygiene, 43(3), 196–200. https://doi.org/10.1017/s002217240001281x
- Miyaoka, Y., Kabir, M. H., Hasan, M. A., Yamaguchi, M., Shoham, D., Murakami, H., & Takehara, K. (2021). Virucidal activity of slightly acidic hypochlorous acid water toward influenza virus and coronavirus with tests simulating practical usage. Virus research, 297, 198383. https://doi.org/10.1016/j.virusres.2021.198383
- Dianty, R., Hirano, J., Anzai, I., Kanai, Y., Hayashi, T., Morimoto, M., Kataoka-Nakamura, C., Kobayashi, S., Uemura, K., Ono, C., Watanabe, T., Kobayashi, T., Murakami, K., Kikuchi, K., Hotta, K., Yoshikawa, T., Taguwa, S., & Matsuura, Y. (2023). Electrolyzed hypochlorous acid water exhibits potent disinfectant activity against various viruses through irreversible protein aggregation. Frontiers in microbiology, 14, 1284274. https://doi.org/10.3389/fmicb.2023.1284274
- Hatanaka, N., Yasugi, M., Sato, T., Mukamoto, M., & Yamasaki, S. (2022). Hypochlorous acid solution is a potent antiviral agent against SARS-CoV-2. Journal of applied microbiology, 132(2), 1496–1502. https://doi.org/10.1111/jam.15284
- Yan, P., Daliri, E. B., & Oh, D. H. (2021). New Clinical Applications of Electrolyzed Water: A Review. Microorganisms, 9(1), 136. https://doi.org/10.3390/microorganisms9010136
- Chen, B. K., & Wang, C. K. (2022). Electrolyzed Water and Its Pharmacological Activities: A Mini-Review. Molecules (Basel, Switzerland), 27(4), 1222. https://doi.org/10.3390/molecules27041222
- Rahman, S., Khan, I., & Oh, D. H. (2016). Electrolyzed Water as a Novel Sanitizer in the Food Industry: Current Trends and Future Perspectives. Comprehensive reviews in food science and food safety, 15(3), 471–490. https://doi.org/10.1111/1541-4337.12200
- Fukuzaki, S. (2023). Uses of gaseous hypochlorous acid for controlling microorganisms in indoor spaces. Journal of microorganism control, 28(4), 165–175. https://doi.org/10.4265/jmc.28.4_165
- Nagamatsu,Y., Nagamatsu, H., Ikeda, H., & Shimizu, H. (2021). Microbicidal effect and storage stability of neutral HOCl-containing aqueous gels with different thickening/gelling agents. Dental materials journal, 40(6), 1309–1319. https://doi.org/10.4012/dmj.2020-454
- Chen, B. K., & Wang, C. K. (2022). Electrolyzed Water and Its Pharmacological Activities: A Mini-Review. Molecules (Basel, Switzerland), 27(4), 1222. https://doi.org/10.3390/molecules27041222
- Stefanello, A., Magrini, L. N., Lemos, J. G., Garcia, M. V., Bernardi, A. O., Cichoski, A. J., & Copetti, M. V. (2020). Comparison of electrolized water and multiple chemical sanitizer action against heat-resistant molds (HRM). International journal of food microbiology, 335, 108856. https://doi.org/10.1016/j.ijfoodmicro.2020.108856
- Gonçalves Lemos, J., Stefanello, A., Olivier Bernardi, A., Valle Garcia, M., Nicoloso Magrini, L., Cichoski, A. J., Wagner, R., & Venturini Copetti, M. (2020). Antifungal efficacy of sanitizers and electrolyzed waters against toxigenic Aspergillus. Food research international (Ottawa, Ont.), 137, 109451. https://doi.org/10.1016/j.foodres.2020.109451
- Ishihara, M., Murakami, K., Fukuda, K., Nakamura, S., Kuwabara, M., Hattori, H., Fujita, M., Kiyosawa, T., & Yokoe, H. (2017). Stability of Weakly Acidic Hypochlorous Acid Solution with Microbicidal Activity. Biocontrol science, 22(4), 223–227. https://doi.org/10.4265/bio.22.223
- Ono, T., Yamashita, K., Murayama, T., & Sato, T. (2012). Microbicidal effect of weak acid hypochlorous solution on various microorganisms. Biocontrol science, 17(3), 129–133. https://doi.org/10.4265/bio.17.129
- Fukuzaki S. (2006). Mechanisms of actions of sodium hypochlorite in cleaning and disinfection processes. Biocontrol science, 11(4), 147–157. https://doi.org/10.4265/bio.11.147
- Jeong, S. H., Kim, W., & Kwon, J. H. (2024). Development of a new sterilization method for microalgae media using calcium hypochlorite as the sterilant. Bioprocess and biosystems engineering, 47(3), 393–401. https://doi.org/10.1007/s00449-024-02971-z
- Stubbs, A. D., Lao, M., Wang, C., Abbatt, J. P. D., Hoffnagle, J., VandenBoer, T. C., & Kahan, T. F. (2023). Near-source hypochlorous acid emissions from indoor bleach cleaning. Environmental science. Processes & impacts, 25(1), 56–65. https://doi.org/10.1039/d2em00405d
- Lu, M. C., Chen, P. L., Huang, D. J., Liang, C. K., Hsu, C. S., & Liu, W. T (2021). Disinfection efficiency of hospital infectious disease wards with chlorine dioxide and hypochlorous acid. Aerobiologia, 37(1), 29–38. https://doi.org/10.1007/s10453-020-09670-8
- Boecker, D., Zhang, Z., Breves, R., Herth, F., Kramer, A., & Bulitta, C. (2023). Antimicrobial efficacy, mode of action and in vivo use of hypochlorous acid (HOCl) for prevention or therapeutic support of infections. GMS hygiene and infection control, 18, Doc07. https://doi.org/10.3205/dgkh000433
- Wong, J. P. S., Carslaw, N., Zhao, R., Zhou, S., & Abbatt, J. P. D. (2017). Observations and impacts of bleach washing on indoor chlorine chemistry. Indoor air, 27(6), 1082–1090. https://doi.org/10.1111/ina.12402
- Wang, L., Bassiri, M., Najafi, R., Najafi, K., Yang, J., Khosrovi, B., Hwong, W., Barati, E., Belisle, B., Celeri, C., & Robson, M. C. (2007). Hypochlorous acid as a potential wound care agent: part I. Stabilized hypochlorous acid: a component of the inorganic armamentarium of innate immunity. Journal of burns and wounds, 6, e5.
- Stroman, D. W., Mintun, K., Epstein, A. B., Brimer, C. M., Patel, C. R., Branch, J. D., & Najafi-Tagol, K. (2017). Reduction in bacterial load using hypochlorous acid hygiene solution on ocular skin. Clinical Ophthalmology (Auckland, N.Z.), 11, 707-714. https://doi.org/10.2147/OPTH.S132851
- Overholt, B., Reynolds, K., & Wheeler, D. (2018). 1151. A Safer, More Effective Method for Cleaning and Disinfecting GI Endoscopic Procedure Rooms. Open Forum Infectious Diseases, 5(Suppl1), S346. https://doi.org/10.1093/ofid/ofy210.984
- Gon, G., Dansero, L., Aiken, A. M., Bottomley, C., Dancer, S. J., Graham, W. J., Ike, O. C., Lewis, M., Meakin, N., Okafor, O., Uwaezuoke, N. S., & Okwor, T. J. (2022). A Better Disinfectant for Low-Resourced Hospitals? A Multi-Period Cluster Randomised Trial Comparing Hypochlorous Acid with Sodium Hypochlorite in Nigerian Hospitals: The EWASH Trial. Microorganisms, 10(5),
910. https://doi.org/10.3390/microorganisms10050910 - Meakin, N. S., Bowman, C., Lewis, M. R., & Dancer, S. J. (2012). Comparison of cleaning efficacy between in-use disinfectant and electrolysed water in an English residential care home. The Journal of hospital infection, 80(2), 122–127. https://doi.org/10.1016/j.jhin.2011.10.015
- Gessa Sorroche, M., Relimpio López, I., García-Delpech, S., & Benítez Del Castillo, J. M. (2022). Hypochlorous acid as an antiseptic in the care of patients with suspected COVID-19 infection. Archivos de la Sociedad Espanola de Oftalmologia, 97(2), 77–80. https://doi.org/10.1016/j.oftale.2021.01.010
- Kim, H. J., Lee, J. G., Kang, J. W., Cho, H. J., Kim, H. S., Byeon, H. K., & Yoon, J. H. (2008). Effects of a low concentration hypochlorous Acid nasal irrigation solution on bacteria, fungi, and virus. The Laryngoscope, 118(10), 1862–1867. https://doi.org/10.1097/MLG.0b013e31817f4d34
- Palau, M., Muñoz, E., Lujan, E., Larrosa, N., Gomis, X., Márquez, E., Len, O., Almirante, B., Abellà, J., Colominas, S., & Gavaldà, J. (2022). In Vitro and In Vivo Antimicrobial Activity of Hypochlorous Acid against Drug-Resistant and Biofilm-Producing Strains. Microbiology spectrum, 10(5), e0236522. https://doi.org/10.1128/spectrum.02365-22
- Duan, X., Wang, X., Xie, Y., Yu, P., Zhuang, T., Zhang, Y., Fang, L., Ping, Y., Liu, W., & Tao, Z. (2021). High concentrations of hypochlorous acid-based disinfectant in the environment reduced the load of SARS-CoV-2 in nucleic acid amplification testing. Electrophoresis, 42(14-15), 1411–1418. https://doi.org/10.1002/elps.202000387
- World Health Organization. (2020). Cleaning and disinfection of environmental surfaces in the context of COVID-19: interim guidance, 15 May 2020 (No.WHO/2019-nCoV/Disinfection/2020.1). World Health Organization.
- Nguyen, K., Bui, D., Hashemi, M., Hocking, D. M., Mendis, P., Strugnell, R. A., & Dharmage, S. C. (2021). The Potential Use of Hypochlorous Acid and a Smart Prefabricated Sanitising Chamber to Reduce Occupation-Related COVID-19 Exposure. Risk management and healthcare policy, 14, 247–252. https://doi.org/10.2147/RMHP.S284897
- Dianty, R., Hirano, J., Anzai, I., Kanai, Y., Hayashi, T., Morimoto, M., Kataoka-Nakamura, C., Kobayashi, S., Uemura, K., Ono, C., Watanabe, T., Kobayashi, T., Murakami, K., Kikuchi, K., Hotta, K., Yoshikawa, T., Taguwa, S., & Matsuura, Y. (2023). Electrolyzed hypochlorous acid water exhibits potent disinfectant activity against various viruses through irreversible protein aggregation. Frontiers in microbiology, 14, 1284274. https://doi.org/10.3389/fmicb.2023.1284274
- Yan, P., Chelliah, R., Jo, K. H., & Oh, D. H. (2021). Research Trends on the Application of Electrolyzed Water in Food Preservation and Sanitation. Processes, 9(12), 2240. https://doi.org/10.3390/pr9122240
- Fukuzaki S. (2006). Mechanisms of actions of sodium hypochlorite in cleaning and disinfection processes. Biocontrol science, 11(4), 147–157. https://doi.org/10.4265/bio.11.147
- Jan, A., Chen, M., Nijboer, M., Luiten-Olieman, M. W. J., Rietveld, L. C., & Heijman, S. G. J. (2024). Effect of Long-Term Sodium Hypochlorite Cleaning on Silicon Carbide Ultrafiltration Membranes Prepared via Low-Pressure Chemical Vapor Deposition. Membranes, 14(1), 22. https://doi.org/10.3390/membranes14010022
- Sivamani Chidambaram, R., Rajmohan, S., Olive Prasad, P., Kalyani, D., Mallikarjuna, R., & Ganiga Channaiah, S. (2024). Evaluation of the Effectiveness of Disinfectants on Impression Materials. Cureus, 16(2), e54846. https://doi.org/10.7759/cureus.54846
- da Cruz Nizer, W. S., Inkovskiy, V., & Overhage, J. (2020). Surviving Reactive Chlorine Stress: Responses of Gram-Negative Bacteria to Hypochlorous Acid. Microorganisms, 8(8), 1220. https://doi.org/10.3390/microorganisms8081220
- Farah, R. I., & Al-Haj Ali, S. N. (2021). Electrolyzed Water Generated On-Site as a Promising Disinfectant in the Dental Office During the COVID-19 Pandemic. Frontiers in public health, 9, 629142. https://doi.org/10.3389/fpubh.2021.629142
- Gessi, A., Formaglio, P., Semeraro, B., Summa, D., Tamisari, E., & Tamburini, E. (2023). Electrolyzed Hypochlorous Acid (HOCl) Aqueous Solution as Low-Impact and Eco-Friendly Agent for Floor Cleaning and Sanitation. International journal of environmental research and public health, 20(18), 6712. https://doi.org/10.3390/ijerph20186712
- Dewi, F. R., Stanley, R., Powell, S. M., & Burke, C. M. (2017). Application of electrolysed oxidising water as a sanitiser to extend the shelf-life of seafood products: a review. Journal of food science and technology, 54(5), 1321–1332.
https://doi.org/10.1007/s13197-017-2577-9 - Iram, A., Wang, X., & Demirci, A. (2021). Electrolyzed Oxidizing Water and Its Applications as Sanitation and Cleaning Agent. Food Engineering Reviews, 13(2), 411–427. https://doi.org/10.1007/s12393-021-09278-9
- Naka, A., Yakubo, M., Nakamura, K., & Kurahashi, M. (2020). Effectiveness of slightly acidic electrolyzed water on bacteria reduction: in vitro and spray evaluation. PeerJ, 8, e8593. https://doi.org/10.7717/peerj.8593
- Veasey, S., & Muriana, P. M. (2016). Evaluation of Electrolytically-Generated Hypochlorous Acid ('Electrolyzed Water') for Sanitation of Meat and Meat-Contact Surfaces. Foods (Basel, Switzerland), 5(2), 42. https://doi.org/10.3390/foods5020042
- Parveen, N., Chowdhury, S., & Goel, S. (2022). Environmental impacts of the widespread use of chlorine-based disinfectants during the COVID-19 pandemic. Environmental Science and Pollution Research International, 29(57), 85742-85760. https://doi.org/10.1007/s11356-021-18316-2
- National Research Council (US) Safe Drinking Water Committee. Drinking Water and Health: Disinfectants and Disinfectant By-Products: Volume 7. Washington (DC): National Academies Press (US); 1987. 2, Disinfection Methods and Efficacy. Available from: https://www.ncbi.nlm.nih.gov/books/NBK217999/
- Khalaf, B. S., Abass, S. M., Al-Khafaji, A. M., & Issa, M. I. (2023). Antimicrobial Efficiency of Hypochlorous Acid and Its Effect on Some Properties of Alginate Impression Material. International Journal of Dentistry, 2023. https://doi.org/10.1155/2023/8584875
- Parveen, N., Chowdhury, S., & Goel, S. (2022). Environmental impacts of the widespread use of chlorine-based disinfectants during the COVID-19 pandemic. Environmental science and pollution research international, 29(57), 85742–85760. https://doi.org/10.1007/s11356-021-18316-2
- Guidelines for drinking-water quality: Fourth edition incorporating the first and second addenda [Internet]. Geneva: World Health Organization; 2022. ANNEX 5, Treatment methods and performance. Available from: https://www.ncbi.nlm.nih.gov/books/NBK579455/
- GOTO, K., KUWAYAMA, E., NOZU, R., UENO, M., & HAYASHIMOTO, N. (2015). Effect of hypochlorous acid solution on the eradication and prevention of Pseudomonas aeruginosa infection, serum biochemical variables, and cecum microbiota in rats. Experimental Animals, 64(2), 191-197. https://doi.org/10.1538/expanim.14-0068
Tea Tree and Eucalyptus Oil Scientific Studies
Scientific Studies
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- Romeo, A., Iacovelli, F., Scagnolari, C., Scordio, M., Frasca, F., Condò, R., Ammendola, S., Gaziano, R., Anselmi, M., Divizia, M., & Falconi, M.(2022). Potential Use of Tea Tree Oil as a Disinfectant Agent against Coronaviruses: A Combined Experimental and Simulation Study. Molecules (Basel, Switzerland), 27(12), 3786. https://doi.org/10.3390/molecules27123786
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Toilet Bomb Scientific Studies
Scientific Studies
- Dennler-Church, T. E., Butz, J. C., McKinley, J. E., Keim, E. K., Hall, M. C., Meschke, J. S., Mulligan, J. M., Williams, J. F., & Robins, L. I. (2020). Modification of Major Contributors Responsible for Latrine Malodor on Exposure to Hypochlorous Acid: The Potential for Simultaneously Impacting Odor and Infection Hazards to Encourage Latrine Use. The American journal of tropical medicine and hygiene, 103(6), 2584–2590. https://doi.org/10.4269/ajtmh.20-0553
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